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Chromaster 5610 MS Detector is a mass detector with new concept, designed for LC users, and it is different from conventional mass spectrometers. This time, the analysis example of triclosan is introduced here. Triclosan is used as a disinfectant for general bacteria in wide range of products including health care products such as medicated soap and toothpaste and plastic and fabric products such as children’s toys. No complex condition setting is required for 5610 MS Detector and thus, mass information can be obtained and a calibration curve can be generated with the operability equivalent to that for UV detectors.