Routine development of multi-component 'Fast Liquid Chromatography' (Fast LC) applications are rapidly and easily accomplished by integrating (a) the new Hitachi LaChrom Elite HPLC system, (b) Automated Method Development tools (ChromSword AUTO), and (c) Hitachi Chromolith monolithic reversed-phase columns. These Fast LC applications allow for high-throughput analyses leading to a significant reduction in run times contrasted to conventional C18 particulate column run times by several-fold. Examples presentedin this articledemonstrate an integrated approach to Fast LC applications development of Over-the-Counter (OTC) analgesics and steroids. (Published in LCGC North America, February 2003. 101 KB)
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